11/21/2023 0 Comments Chaperone def![]() įour forms of autophagy have been identified: macroautophagy, microautophagy, chaperone-mediated autophagy (CMA), and crinophagy. Defects in autophagy have been linked to various human diseases, including neurodegeneration and cancer, and interest in modulating autophagy as a potential treatment for these diseases has grown rapidly. Although initially characterized as a primordial degradation pathway induced to protect against starvation, it has become increasingly clear that autophagy also plays a major role in the homeostasis of non-starved cells. It allows the orderly degradation and recycling of cellular components. A Diagram of the process of autophagy, which produces the structures autophagosomes (AP), and autolysosomes (AL) B Electron micrograph of autophagic structures AP and AL in the fat body of a fruit fly larva C Fluorescently-labeled autophagosomes AP in liver cells of starved mice.Īutophagy (or autophagocytosis from the Ancient Greek αὐτόφαγος, autóphagos, meaning "self-devouring" and κύτος, kýtos, meaning "hollow") is the natural, conserved degradation of the cell that removes unnecessary or dysfunctional components through a lysosome-dependent regulated mechanism. For other uses, see Autophagy (disambiguation). Send us feedback about these examples.This article is about the cellular process. These examples are programmatically compiled from various online sources to illustrate current usage of the word 'chauffeur.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Kenny Herzog, Vulture, 2 June 2023 See More offices… in an incognito grocery delivery truck. ![]() Rachel Cormack, Robb Report, 11 July 2023 Snapshots of said pit have been purchased by Rolling Stone for exclusive publication, which means Brooke has to chauffeur a flash drive of the hot cargo cross-country to the mag’s L.A. Margaret Coker, ProPublica, 13 July 2023 Guests will be chauffeured between the two destinations in a private helicopter, no less. Stephanie Gallman Jordan, Southern Living, 23 July 2023 Jamal McRae works for a transportation company that chauffeurs Medicaid patients for doctors’ appointments in larger Valdosta or Savannah. 2023 He was chauffeured through the course and got out at the end of the race to cross the finish line on foot. Sarah Matusek, The Christian Science Monitor, 2 Aug. 2023 Laura chauffeurs her son and daughter there on a recent afternoon, the pair chattering away in the back seat. 2023 For the intimate ceremony, the pair recited personal vows in front of about 30 guests, who had been chauffeured to the estate. 2023 That’s a drawback in the Chinese market, where wealthy customers often prefer to be chauffeured. Joey Capparella, Car and Driver, 6 Sep. Verb The Century sedan has existed for many decades and is a highly exclusive model only for Japan meant for chauffeuring important people. Jane Bradley, New York Times, 27 July 2023 Safety and Driver-Assistance Features A suite of high-tech driver-assistance features is standard to give your chauffeur a hand on long trips. 2023 The British government has allowed Russian oligarchs to spend hundreds of thousands of dollars on perks like private chefs, chauffeurs and housekeepers, despite ostensibly having their bank accounts frozen, documents show. 2023 The school district is actively hiring for full-time and part-time bus drivers, bus attendants and van chauffeurs, according to its hiring website. 2023 The son of a Senegalese immigrant, Diop initially set out to avenge the wrongful imprisonment and death of his father, a chauffeur/butler who was framed by his duplicitous, aristocratic employer. 2023 An inquest in 2008 concluded that reckless driving by chauffeur Henri Paul and the pursuit of paparazzi combined to cause the crash. ![]() 2023 Big Walter’s son, Walter Lee Younger (Singletary), is a chauffeur in his mid-30s who is chafing at the narrow constraints of his existence. 2023 The inquest ruled that Diana and Dodi were unlawfully killed by the grossly negligent driving of their chauffeur while being pursued through a Paris road tunnel by photographers. Noun Work in auto plants provided an advancement for Black people who had been disproportionately restricted to such jobs as domestics, chauffeurs, custodians and farm laborers, according to Sugrue's report.
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